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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNB1
All Species:
35.15
Human Site:
Y709
Identified Species:
59.49
UniProt:
P35222
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35222
NP_001091679.1
781
85497
Y709
A
Q
G
E
P
L
G
Y
R
Q
D
D
P
S
Y
Chimpanzee
Pan troglodytes
XP_001137676
774
84747
Y702
A
Q
G
E
P
L
G
Y
R
Q
D
D
P
S
Y
Rhesus Macaque
Macaca mulatta
XP_001115474
511
55731
D457
H
S
G
G
Y
G
Q
D
A
L
G
M
D
P
M
Dog
Lupus familis
XP_850439
744
81740
I686
W
E
A
A
Q
S
M
I
P
I
N
E
P
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q02248
781
85452
Y709
A
Q
G
E
A
L
G
Y
R
Q
D
D
P
S
Y
Rat
Rattus norvegicus
Q9WU82
781
85436
Y709
A
Q
G
E
A
L
G
Y
R
Q
D
D
P
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516985
781
85506
Y709
A
Q
G
E
P
L
G
Y
R
Q
D
D
P
S
Y
Chicken
Gallus gallus
NP_990412
781
85420
Y709
A
Q
G
E
P
L
G
Y
R
P
D
D
P
S
Y
Frog
Xenopus laevis
P26233
781
85431
Y709
A
Q
G
E
P
L
G
Y
R
Q
D
D
S
S
Y
Zebra Danio
Brachydanio rerio
NP_571134
780
85502
Y708
A
Q
G
E
P
L
G
Y
R
Q
D
D
P
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18824
843
91134
S734
L
Y
G
Q
G
P
P
S
V
H
S
S
H
G
G
Honey Bee
Apis mellifera
XP_391947
811
88602
Y731
D
Q
G
Y
D
G
M
Y
G
Q
G
P
P
S
V
Nematode Worm
Caenorhab. elegans
O44326
678
74493
Y624
N
M
S
N
S
Y
D
Y
E
M
S
G
S
A
A
Sea Urchin
Strong. purpuratus
NP_001027543
825
89711
Y757
L
H
S
N
H
G
E
Y
R
Q
P
P
P
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
65.4
66.4
N.A.
99.8
99.7
N.A.
99.7
99.3
97.4
97.1
N.A.
65.7
67.6
28.5
67.2
Protein Similarity:
100
99
65.4
77.4
N.A.
99.8
99.7
N.A.
99.8
99.6
99
98.9
N.A.
77.2
80.1
46.4
77.7
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
93.3
N.A.
100
93.3
93.3
100
N.A.
6.6
40
6.6
26.6
P-Site Similarity:
100
100
6.6
26.6
N.A.
93.3
93.3
N.A.
100
93.3
93.3
100
N.A.
13.3
40
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
8
8
15
0
0
0
8
0
0
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
8
8
0
0
58
58
8
0
0
% D
% Glu:
0
8
0
58
0
0
8
0
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
79
8
8
22
58
0
8
0
15
8
0
8
8
% G
% His:
8
8
0
0
8
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
0
0
0
0
58
0
0
0
8
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
15
0
0
8
0
8
0
0
15
% M
% Asn:
8
0
0
15
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
43
8
8
0
8
8
8
15
72
8
0
% P
% Gln:
0
65
0
8
8
0
8
0
0
65
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% R
% Ser:
0
8
15
0
8
8
0
8
0
0
15
8
15
65
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
8
8
0
79
0
0
0
0
0
8
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _